D2-Like Receptor Expression in the Hippocampus and Amygdala Informs Performance on the Stop-Signal Task in Parkinson's Disease

Using PET imaging and a stop-signal task in patients with Parkinson’s disease, we found that greater D2-like receptor binding in the hippocampus and amygdala was associated with faster stopping, pointing to a role for mesolimbic dopamine in response inhibition.

December 2021 · Leah G. Mann, Kaitlyn R. Hay, Alexander K. Song, Steven P. Errington, Paula Trujillo, David H. Zald, Yan Yan, Hakmook Kang, Gordon D. Logan, & Daniel O Claassen